Article
The V kappa genes of the L regions and the repertoire of V kappa gene sequences in the human germ line.
European journal of immunology - 1 Nov 1993
Huber C, Schäble K F, Huber E, Klein R, Meindl A, Thiebe R, Lamm R, Zachau H G
Abstract excerpt
Only 14 of the 25 V kappa genes and pseudogenes had been found before as parts of the L regions. The cloning and linking described in the accompanying report allowed us now to assign to Lp or Ld some V kappa genes which had been found before on scattered clones. In addition the sequences of sever...
Topics
- Alleles
- Amino Acid Sequence
- Antibody Diversity
- Base Sequence
- Biological Evolution
- DNA
- Gene Conversion
- Genes, Immunoglobulin
- Humans
- Immunoglobulin Variable Region
- Immunoglobulin kappa-Chains
- Molecular Sequence Data
- Multigene Family
- Restriction Mapping