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Article

The human immunoglobulin kappa locus: pseudogenes, unique and repetitive sequences.

Biological chemistry Hoppe-Seyler - 1 Mar 1994

Schäble K, Thiebe R, Flügel A, Meindl A, Zachau H G

Abstract excerpt

The human kappa locus contains 25 pseudogenes. After seven of them were described earlier the structures of the remaining 18 are reported now, thus completing the description of all human V kappa genes and pseudogenes. Most of the pseudogenes carry several defects each. Alignments of the pseudogene sequences and comparison with the consensus sequences of the potentially functional V kappa genes indicate that, on...

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PMID: 8011175
DOI: 10.1515/bchm3.1994.375.3.189

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