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Article

Most kappa immunoglobulin mRNA in human lymphocytes is homologous to a small family of germ-line V genes.

Nature - 1 Jan 2000

Bentley D L

Abstract excerpt

The mammalian immune system produces 10(6)-10(8) different antibody-combining sites. It has been established that three factors contribute to the diversity of immunoglobulin variable regions: multiple gene segments in the germ line, somatic recombination of these segments and somatic mutation. However, the relative importance of these components in generating the antibody repertoire is unknown. One way to assess...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 6419127
DOI: 10.1038/307077a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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