Susceptibilities of oxyR regulon mutants of Escherichia coli and Salmonella typhimurium to isoniazid.

doi:10.1128/AAC.37.10.2251

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Article

Susceptibilities of oxyR regulon mutants of Escherichia coli and Salmonella typhimurium to isoniazid.

Antimicrobial agents and chemotherapy - 1 Oct 1993

Rosner J L

Abstract excerpt

Escherichia coli and Salmonella typhimurium are normally resistant to > 500 micrograms of the antituberculosis drug isonicotinic acid hydrazide (isoniazid; INH) per ml. Susceptibility to INH (< 50 micrograms/ml) has now been found for mutants that are deficient in OxyR, the oxidative stress respo...

Topics

Catalase
Escherichia coli
Escherichia coli Proteins
Genes, Bacterial
Isoniazid
Microbial Sensitivity Tests
Mutation
Oxidoreductases
Peroxidases
Peroxiredoxins
Regulon
Salmonella typhimurium

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