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Article

A Salmonella enterica serovar typhimurium hemA mutant is highly susceptible to oxidative DNA damage.

Journal of bacteriology - 1 Jul 2002

Elgrably-Weiss Maya, Park Sunny, Schlosser-Silverman Eliana, Rosenshine Ilan, Imlay James, Altuvia Shoshy

Abstract excerpt

The first committed step in the biosynthesis of heme, an important cofactor of two catalases and a number of cytochromes, is catalyzed by the hemA gene product. Salmonella enterica serovar Typhimurium hemA26::Tn10d (hemA26) was identified in a genetic screen of insertion mutants that were sensitive to hydrogen peroxide. Here we show that the hemA26 mutant respires at half the rate of wild-type cells and is highly...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12081946
DOI: 10.1128/JB.184.14.3774-3784.2002
PMCID: PMC135181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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