Article
Haemophilus influenzae OxyR: characterization of its regulation, regulon and role in fitness.
PloS one - 1 Jan 2012
Whitby Paul W, Morton Daniel J, Vanwagoner Timothy M, Seale Thomas W, Cole Brett K, Mussa Huda J, McGhee Phillip A, Bauer Chee Yoon S, Springer Jennifer M, Stull Terrence L
Abstract excerpt
To prevent damage by reactive oxygen species, many bacteria have evolved rapid detection and response systems, including the OxyR regulon. The OxyR system detects reactive oxygen and coordinates the expression of numerous defensive antioxidants. In many bacterial species the coordinated OxyR-regulated response is crucial for in vivo survival. Regulation of the OxyR regulon of Haemophilus influenzae was examined...
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