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Article

Protective role of the Mycobacterium smegmatis IdeR against reactive oxygen species and isoniazid toxicity.

Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Jan 1998

Dussurget O, Rodriguez M, Smith I

Abstract excerpt

OBJECTIVE: To understand the mechanism by which IdeR is necessary for maintaining wild type levels of KatG and SodA enzyme activity and normal isoniazid (INH) resistance. DESIGN: To identify the step(s) of SodA and KatG function that were affected by the ideR mutation, quantitative western immunoassays and ribonucleic acid (RNA) hybridizations were performed. To see if the increased INH sensitivity of the ideR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10645447
DOI: 10.1054/tuld.1998.0011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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