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Article

T cell receptor V beta gene bias in rheumatoid arthritis.

The Journal of clinical investigation - 1 Dec 1993

Jenkins R N, Nikaein A, Zimmermann A, Meek K, Lipsky P E

Abstract excerpt

Polymerase chain reaction (PCR) technology was employed to examine peripheral blood and synovial T cells in patients with rheumatoid arthritis (RA) for biased utilization of T cell receptor (TCR) variable region (V) genes. Oligonucleotide primers specific for individual TCR V beta gene families were used to amplify TCR gene products in a semiquantitative assay of their relative utilization in unselected T cell...

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Identifiers

PMID: 8254025
DOI: 10.1172/JCI116886
PMCID: PMC288467

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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T cell receptor V beta gene bias in rheumatoid arthritis.PMID 8254025Read ↗

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