Article
An improved methodology to detect human T cell receptor beta variable family gene expression patterns.
Journal of immunological methods - 1 Jul 2005
Brewer Jamie Leigh, Ericson Solveig Gronning
Abstract excerpt
Comprehensive gene expression analysis of the T cell receptor repertoire of an individual can be very useful in evaluating the immune response in a variety of conditions. Antibody-based analysis methods can detect approximately 60% of the human T cell receptor beta variable (TCRBV) proteins, while gene expression analysis, primarily through employment of the polymerase chain reaction (PCR), has had somewhat...
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