Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Restricted expression of T cell receptor V<sub>β</sub> but not V<sub>α</sub> genes in rheumatoid arthritis

1 Feb 1991

Abstract excerpt

Synovial fluids of patients with rheumatoid arthritis contain activated T lymphocytes that may play an important role in the pathogenesis of the disease. Previous studies have suggested that the T cell receptor (TcR) repertoire of these cells is restricted, reflecting in vivo selection of a limited number of T cell specificities at the site of inflammation. To characterize better these T cell populations we used...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Monoclonal and Polyclonal Antibodies Research
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1671839
DOI: 10.1002/eji.1830210231

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Restricted expression of T cell receptor V<sub>β</sub> but not V<sub>α</sub> genes in rheumatoid arthritisPMID 1671839Read ↗

Biased T cell receptor V gene usage in rheumatoid arthritis. Oligoclonal expansion of T cells expressing V alpha 2 genes in synovial fluid but not in peripheral blood.Semantic proximity Read ↗

T cell receptor V beta gene bias in rheumatoid arthritis.Semantic proximity Read ↗

Limited T-cell receptor beta-chain heterogeneity among interleukin 2 receptor-positive synovial T cells suggests a role for superantigen in rheumatoid arthritis.Semantic proximity Read ↗

Direct evidence for the expression of multiple endogenous retroviruses in the synovial compartment in rheumatoid arthritisSemantic proximity Read ↗

Aberrations in the primary T-cell receptor repertoire as a predisposition for synovial inflammation in rheumatoid arthritis.Semantic proximity Read ↗

Immunoglobulin V genes in rheumatoid arthritis.Semantic proximity Read ↗

Expression of endogenous retroviruses, ERV3 and λ4–1, in synovial tissues from patients with rheumatoid arthritisSemantic proximity Read ↗

A minor group of rheumatoid factors isolated from a patient with rheumatoid arthritis is derived from somatically mutated Vk1 genes further evidence that rheumatoid factors during autoimmune diseases undergo an antigen driven maturation.Semantic proximity Read ↗

Peripheral blood but not synovial fluid natural killer T cells are biased towards a Th1-like phenotype in rheumatoid arthritis.Semantic proximity Read ↗

The B lymphocyte in rheumatoid arthritis: analysis of rearranged V kappa genes from B cells infiltrating the synovial membrane.Semantic proximity Read ↗

T cell receptor V beta gene usage in the recognition of myelin basic protein by cerebrospinal fluid- and blood-derived T cells from patients with multiple sclerosis.Semantic proximity Read ↗

The immunoglobulin kappa light chain repertoire expressed in the synovium of a patient with rheumatoid arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.