c-N-ras is activated infrequently in canine malignant lymphoma.

doi:10.1177/019262339302100304

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Article

c-N-ras is activated infrequently in canine malignant lymphoma.

Toxicologic pathology - 1 Jan 1993

Edwards M D, Pazzi K A, Gumerlock P H, Madewell B R

Abstract excerpt

Activated c-N-ras alleles have been detected in human lymphoma specimens. The aim of the present study was to determine the frequency of c-N-ras mutational activation in canine malignant lymphoma. DNA was isolated from 28 canine malignant lymphoma specimens collected from 28 separate dogs and exa...

Topics

2,4-Dichlorophenoxyacetic Acid
Animals
Base Sequence
Carcinogens
DNA, Neoplasm
Dog Diseases
Dogs
Exons
Genes, ras
Histocytochemistry
Lymphoma
Mutation
Polymerase Chain Reaction

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