Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RAS, FLT3, and C-KIT mutations in immunophenotyped canine leukemias.

Experimental hematology - 1 Jan 2009

Usher Suzanne G, Radford Alan D, Villiers Elizabeth J, Blackwood Laura

Abstract excerpt

OBJECTIVE: To determine the frequency of FLT3, C-KIT, and RAS mutations in canine leukemia patients. MATERIALS AND METHODS: Ethylenediamine tetra-acetic acid blood samples were recruited from dogs with suspected leukemia, categorized by quantitative and cytological evaluation and immunophenotyping. Flow cytometry was carried out using antibodies against CD3; CD3e; CD4; CD5; CD8; CD11a, b, c, and d; CD14; CD21;...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease
Share to Antigens, CD
Share to Chronic Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dog Diseases

Share to fms-Like Tyrosine Kinase 3

Share to Leukemia

Share to Proto-Oncogene Proteins c-kit

Share to ras Proteins

Source

Identifiers

PMID: 18977066
DOI: 10.1016/j.exphem.2008.09.005

Genes

FLT3
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RAS, FLT3, and C-KIT mutations in immunophenotyped canine leukemias.PMID 18977066Read ↗

Evaluation of tyrosine-kinase receptor c-KIT (c-KIT) mutations, mRNA and protein expression in canine leukemia: might c-KIT represent a therapeutic target?Semantic proximity Read ↗

FLT3 mutations in canine acute lymphocytic leukemia.Semantic proximity Read ↗

Use of the Cell-Dyn 3500 to predict leukemic cell lineage in peripheral blood of dogs and cats.Semantic proximity Read ↗

Evaluation of tyrosine-kinase receptor c-kit mutations, mRNA and protein expression in canine lymphoma: might c-kit represent a therapeutic target?Semantic proximity Read ↗

Diagnosis of canine B-cell chronic lymphoid leukemia with a CD21 negative phenotype using the LT21 clone CD21 antibody in flow cytometry: a case report.Semantic proximity Read ↗

Breed Distribution and Clinical Characteristics of B Cell Chronic Lymphocytic Leukemia in Dogs.Semantic proximity Read ↗

Cytogenetic alterations in eight mammary tumors and tumor-suppressor gene p53 mutation in one mammary tumor from dogs.Semantic proximity Read ↗

Gain-of-function mutations in the extracellular domain of KIT are common in canine mast cell tumors.Semantic proximity Read ↗

Activating FLT3 mutations in CD117/KIT+ T-cell acute lymphoblastic leukemiasSemantic proximity Read ↗

Constitutive Kit activity triggers B-cell acute lymphoblastic leukemia-like disease in mice.Semantic proximity Read ↗

Nucleotide sequence of canine c-N-ras: codons 1 to 71.Semantic proximity Read ↗

Aberrations of the p53 tumor suppressor gene in various tumors in dogsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.