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Article

RAS, FLT3, and C-KIT mutations in immunophenotyped canine leukemias.

Experimental hematology - 1 Jan 2009

Usher Suzanne G, Radford Alan D, Villiers Elizabeth J, Blackwood Laura

Abstract excerpt

OBJECTIVE: To determine the frequency of FLT3, C-KIT, and RAS mutations in canine leukemia patients. MATERIALS AND METHODS: Ethylenediamine tetra-acetic acid blood samples were recruited from dogs with suspected leukemia, categorized by quantitative and cytological evaluation and immunophenotyping. Flow cytometry was carried out using antibodies against CD3; CD3e; CD4; CD5; CD8; CD11a, b, c, and d; CD14; CD21;...

Topics

Acute Disease
Animals
Antigens, CD
Chronic Disease
Dog Diseases
Dogs
Leukemia
Mutation
Proto-Oncogene Proteins c-kit
fms-Like Tyrosine Kinase 3
ras Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18977066
DOI: 10.1016/j.exphem.2008.09.005

Genes

FLT3
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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