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Article

Mutation of p53 Gene and Its Correlation with the Clinical Outcome in Dogs with Lymphoma.

Journal of veterinary internal medicine - 1 Jan 2000

Koshino A, Goto-Koshino Y, Setoguchi A, Ohno K, Tsujimoto H

Abstract excerpt

BACKGROUND: p53 plays a key role in the apoptotic event induced by chemotherapeutic agents. Mutation of p53 gene has been observed in various spontaneous tumors in humans and is associated with a poor prognosis. p53 abnormalities have been evaluated in several tumors in dogs; however, the association of p53 gene mutation with clinical outcome in dogs with lymphoma has not been documented. HYPOTHESIS/OBJECTIVES:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

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Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 26678182
DOI: 10.1111/jvim.13807
PMCID: PMC4913626

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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