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Article

Positive association between a glutathione-S-transferase polymorphism and lymphoma in dogs.

Veterinary and comparative oncology - 1 Sept 2014

Ginn J, Sacco J, Wong Y Y, Motsinger-Reif A, Chun R, Trepanier L A

Abstract excerpt

Glutathione-S-transferase enzymes (GSTs) play an important role in the detoxification of environmental carcinogens. Defective GST genotypes are over-represented in human cancers; in particular, low activity GSTT1 genotypes are risk factors for non-Hodgkin lymphoma. We hypothesized that defective GSTT1 genotypes would be associated with lymphoma risk in dogs. To address this, we resequenced the exons, splice...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23020265
DOI: 10.1111/vco.12000

Genes

GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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