RAS is required for epidermal growth factor-stimulated arachidonic acid release in rat-1 fibroblasts.

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Article

RAS is required for epidermal growth factor-stimulated arachidonic acid release in rat-1 fibroblasts.

Oncogene - 1 Dec 1993

Warner L C, Hack N, Egan S E, Goldberg H J, Weinberg R A, Skorecki K L

Abstract excerpt

Previous studies have provided suggestive evidence for an interaction between ras activation and signalling pathways involved in agonist-stimulated arachidonic acid release in a variety of cell systems. In order to clarify this interaction, we have measured epidermal growth factor (EGF)-stimulate...

Topics

Animals
Arachidonic Acids
Calcium-Calmodulin-Dependent Protein Kinases
Cell Line
Epidermal Growth Factor
ErbB Receptors
Fibroblasts
Gene Expression Regulation
Genes, ras
Mutation
Phospholipases A
Phospholipases A2
Phosphorylation
Precipitin Tests
Rats
Tetradecanoylphorbol Acetate
Transfection
Tritium

Source

Open in PubMed

Identifiers

PMID: 8247528

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8247528-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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