Article
Evidence for a Ras-dependent extracellular signal-regulated protein kinase (ERK) cascade.
Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1992
Robbins D J, Cheng M, Zhen E, Vanderbilt C A, Feig L A, Cobb M H
Abstract excerpt
The small GTP-binding protein Ras appears to be required for transformation and differentiation induced by tyrosine kinases. The Ras requirement may be limited to a few tyrosine kinase-regulated signaling pathways or may be universal for all tyrosine kinase actions. Because both Ras and the micro...
Topics
- Aluminum
- Aluminum Compounds
- Animals
- Fluorides
- Fluorine
- GTPase-Activating Proteins
- Genes, ras
- Kinetics
- Mitogen-Activated Protein Kinase 1
- Mitogen-Activated Protein Kinase 3
- Mitogen-Activated Protein Kinases
- Mutation
- Nerve Growth Factors
- PC12 Cells
- Phosphorylation
- Protein Kinases
- Proteins
- Retroviridae