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Article

Overexpression of RasN17 fails to neutralize endogenous Ras in MCF7 breast cancer cells.

Journal of biochemistry - 1 Jun 2005

Yuste Laura, Esparís-Ogando Azucena, Santos Eugenio, Pandiella Atanasio

Abstract excerpt

Receptor tyrosine kinases of the ErbB family have been implicated in the onset/progression of a number of neoplasias. In these diseases, ErbB receptor expression may be accompanied by constitutive activation caused by molecular alterations, overexpression, or ligand binding. An important signaling route activated by these receptors that has been linked to the stimulation of cell proliferation is the Ras route....

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PMID: 16002995
DOI: 10.1093/jb/mvi092

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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