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Article

Multiple sites on IL-8 responsible for binding to alpha and beta IL-8 receptors.

Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 1993

Schraufstätter I U, Barritt D S, Ma M, Oades Z G, Cochrane C G

Abstract excerpt

To define the structural features important for IL-8 binding to its two known receptors, mutants of IL-8 and melanoma growth-stimulating activity (MGSA) and chimerae consisting of segments of these two chemokines were constructed and purified from the pGEX 2T Escherichia coli expression vector. IL-8 alpha and beta receptors were expressed stably and individually in 293 kidney epithelial cells and HL60 human...

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PMID: 8245475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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