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Article

Identification of primary structural features that define the differential actions of IL-3 and GM-CSF receptors.

Blood - 1 Nov 2002

Evans Caroline A, Ariffin Shahrul, Pierce Andrew, Whetton Anthony D

Abstract excerpt

Activation of human interleukin 3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF) receptors, ectopically expressed in FDCP-mix multipotent cells, stimulates self-renewal or myeloid differentiation, respectively. These receptors are composed of unique alpha subunits that interact with common beta(c) subunits. A chimeric receptor (hGM/beta(c)), comprising the extracellular domain of the hGM-CSF...

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Identifiers

PMID: 12384414
DOI: 10.1182/blood-2001-12-0235

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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