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The β Common Cytokine Receptor Family Reveals New Functional Paradigms From Structural Complexities

1 Jan 2025

Abstract excerpt

Cytokines are small proteins that are critical for controlling the growth and activity of hematopoietic cells by binding to cell surface receptors and transmitting signals across membranes. The β common (βc) cytokine receptor family, consisting of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3, and IL-5 cytokine receptors, is an architype of the heterodimeric cytokine receptor...

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PMID: 39748163
DOI: 10.1111/imr.13430

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