Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-performance liquid chromatography determination of dextromethorphan and dextrorphan for oxidation phenotyping by fluorescence and ultraviolet detection.

Therapeutic drug monitoring - 1 Aug 1993

Lam Y W, Rodriguez S Y

Abstract excerpt

To establish the usefulness of fluorescence detection to quantify urinary concentrations of dextromethorphan and dextrorphan for oxidation phenotyping, we determined the molar concentration ratio of dextromethorphan to dextrorphan in 38 subjects by UV and fluorescence detection. Dextromethorphan and dextrorphan concentrations were quantified after overnight hydrolysis of urine samples and organic solvent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, High Pressure Liquid
Share to Cytochrome P-450 CYP2D6

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytochrome P-450 Enzyme System

Share to Mixed Function Oxygenases

Share to Oxidation-Reduction

Share to Phenotype

Share to Spectrometry, Fluorescence

Share to Spectrophotometry, Ultraviolet

Source

Identifiers

PMID: 8236365
DOI: 10.1097/00007691-199308000-00007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-performance liquid chromatography determination of dextromethorphan and dextrorphan for oxidation phenotyping by fluorescence and ultraviolet detection.PMID 8236365Read ↗

Determination of dextromethorphan and its O-demethylated metabolite from urine.Semantic proximity Read ↗

Development of an ELISA to study the polymorphism of dextromethorphan oxidation in a French population.Semantic proximity Read ↗

Development of a rapid and sensitive high-performance liquid chromatographic method to determine CYP2D6 phenotype in human liver microsomes.Semantic proximity Read ↗

CYP2D6 genotype and phenotyping by determination of dextromethorphan and metabolites in serum of healthy controls and of patients under psychotropic medication.Semantic proximity Read ↗

Dose dependency of dextromethorphan for cytochrome P450 2D6 (CYP2D6) phenotyping.Semantic proximity Read ↗

Modified high-performance liquid chromatographic method to measure both dextromethorphan and proguanil for oxidative phenotyping.Semantic proximity Read ↗

Quantification of dextromethorphan and metabolites: a dual phenotypic marker for cytochrome P450 3A4/5 and 2D6 activity.Semantic proximity Read ↗

A rapid thin layer chromatographic procedure to identify poor and extensive oxidative drug metabolizers in man using dextromethorphan.Semantic proximity Read ↗

Polymorphism of dextromethorphan oxidation in South Indian subjects.Semantic proximity Read ↗

Dextromethorphan O-demethylation polymorphism in an African-American population.Semantic proximity Read ↗

Serum dextromethorphan/dextrorphan metabolic ratio for CYP2D6 phenotyping in clinical practice.Semantic proximity Read ↗

Dextromethorphan phenotyping and haloperidol disposition in schizophrenic patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.