Article
Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast.
Genes & development - 1 Nov 1993
Yan H, Merchant A M, Tye B K
Abstract excerpt
MCM2 and MCM3 are two genetically interacting and structurally related proteins essential for growth in Saccharomyces cerevisiae. Mutants defective in these proteins affect the stability of minichromosomes in general, but the severity of the defect is dependent on the autonomously replicating seq...
Topics
- Cell Cycle
- Cell Cycle Proteins
- Cell Nucleus
- Chromatography, Affinity
- Chromosomal Proteins, Non-Histone
- Chromosomes, Fungal
- Cloning, Molecular
- DNA Replication
- DNA, Fungal
- Escherichia coli
- Fungal Proteins
- Genotype
- Mutagenesis
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins