Article
Nuclear localization of Schizosaccharomyces pombe Mcm2/Cdc19p requires MCM complex assembly.
Molecular biology of the cell - 1 Dec 1999
Pasion S G, Forsburg S L
Abstract excerpt
The minichromosome maintenance (MCM) proteins MCM2-MCM7 are conserved eukaryotic replication factors that assemble in a heterohexameric complex. In fission yeast, these proteins are nuclear throughout the cell cycle. In studying the mechanism that regulates assembly of the MCM complex, we analyzed the cis and trans elements required for nuclear localization of a single subunit, Mcm2p. Mutation of any single mcm...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
