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Article

The phenotype of the minichromosome maintenance mutant mcm3 is characteristic of mutants defective in DNA replication.

Molecular and cellular biology - 1 Nov 1990

Gibson S I, Surosky R T, Tye B K

Abstract excerpt

MCM3 is an essential gene involved in the maintenance of minichromosomes in yeast cells. It encodes a protein of 971 amino acids that shows striking homology to the Mcm2 protein. We have mapped the mcm3-1 mutation of the left arm of chromosome V approximately 3 kb centromere proximal of anp1. The mcm3-1 mutant was found to be thermosensitive for growth. Under permissive growth conditions, it was defective in...

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Identifiers

PMID: 2233713
DOI: 10.1128/mcb.10.11.5707-5720.1990
PMCID: PMC361340

Genes

MCM3

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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The phenotype of the minichromosome maintenance mutant mcm3 is characteristic of mutants defective in DNA replication.PMID 2233713Read ↗

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