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Article

The HIR4-1 mutation defines a new class of histone regulatory genes in Saccharomyces cerevisiae.

Genetics - 1 Sept 1993

Spector M S, Osley M A

Abstract excerpt

Both activation and repression have been implicated in the cell cycle-regulated transcription of the histone HTA1-HTB1 locus in Saccharomyces cerevisiae. Transcriptional repressors have been identified through the isolation of recessive mutations in the HIR1, HIR2 and HIR3 genes. These three regu...

Topics

Cell Cycle
Gene Expression Regulation, Fungal
Genes, Dominant
Genes, Fungal
Genes, Regulator
Histones
Mutation
Phenotype
Promoter Regions, Genetic
Saccharomyces cerevisiae
Transcription, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8224824
DOI: 10.1093/genetics/135.1.25
PMCID: PMC1205623

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8224824-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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