Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A human homolog of the S.cerevisiae HIR1 and HIR2 transcriptional repressors cloned from the DiGeorge syndrome critical region

1 May 1995

Abstract excerpt

The DiGeorge syndrome (DGS) is a developmental disorder affecting derivatives of the third and fourth pharyngeal pouches. DGS patients present an interstitial deletion in one of their two chromosomes 22. Cosmid DAC30 was mapped to the DGS smallest critical region. Iterative cDNA library screening initiated with a DAC30 gene fragment candidate yielded a cDNA contig whose assembled nucleotide sequence is consistent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycosylation and Glycoproteins Research
Share to Hearing, Cochlea, Tinnitus, Genetics
Share to Salivary Gland Disorders and Functions

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7633437
DOI: 10.1093/hmg/4.5.791

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A human homolog of the S.cerevisiae HIR1 and HIR2 transcriptional repressors cloned from the DiGeorge syndrome critical regionPMID 7633437Read ↗

Human Genome and Diseases: Review¶Transcription factor GATA3 and the human HDR syndromeSemantic proximity Read ↗

Isolation and characterization of a novel gene deleted in DiGeorge syndromeSemantic proximity Read ↗

WHSC1, a 90 kb SET Domain-Containing Gene, Expressed in Early Development and Homologous to a Drosophila Dysmorphy Gene Maps in the Wolf-Hirschhorn Syndrome Critical Region and is Fused to IgH in t(1;14) Multiple MyelomaSemantic proximity Read ↗

Separation-of-function mutation in HPC2, a member of the HIR complex in S. cerevisiae, results in derepression of the histone genes but does not confer cryptic TATA phenotypes.Semantic proximity Read ↗

A common cis-acting sequence in the DiGeorge critical region regulates bi-directional transcription of UFD1L and CDC45L.Semantic proximity Read ↗

A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae.Semantic proximity Read ↗

The HIR4-1 mutation defines a new class of histone regulatory genes in Saccharomyces cerevisiae.Semantic proximity Read ↗

A transcription map of the DiGeorge and velo-cardio-facial syndrome minimal critical region on 22q11Semantic proximity Read ↗

Snrnp25 is a candidate for the peri-implantation lethal phenotype of the Hba deletions.Semantic proximity Read ↗

Assembly, annotation, and integration of UNIGENE clusters into the human genome draft.Semantic proximity Read ↗

Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1Semantic proximity Read ↗

The budding yeast U5 snRNP Prp8 is a highly conserved protein which links RNA splicing with cell cycle progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.