Article
Decreased expression of specific genes in yeast cells lacking histone H1.
The Journal of biological chemistry - 27 Apr 2001
Hellauer K, Sirard E, Turcotte B
Abstract excerpt
Chromatin plays an important role in regulating eukaryotic gene expression. Chromatin is composed of DNA wrapped around a nucleosome core (consisting of two copies of the well conserved histones H2A, H2B, H3, and H4) and a more variable linker histone H1. Various in vitro and in vivo studies have implicated histone H1 as a repressor of gene expression or as an activator, but its exact role is still unclear....
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