Article
Production of the metastatic phenotype by DNA transfection in a rat mammary model.
Cell biology international - 1 Sept 1993
Davies B R, Barraclough R, Davies M P, Rudland P S
Abstract excerpt
A syngeneic, immunocompetent rat mammary model has been employed to investigate the molecular basis of the metastatic phenotype. Transfection of the benign rat mammary epithelial cell line Rama 37 with the gene for p9Ka; a small, rat, calcium-binding protein or DNA from metastatic human cell line...
Topics
- Animals
- Breast Neoplasms
- Calcium-Binding Proteins
- Cell Transformation, Neoplastic
- DNA, Complementary
- DNA, Neoplasm
- Female
- Fibroblast Growth Factor 2
- Humans
- Mammary Glands, Animal
- Mammary Neoplasms, Experimental
- Neoplasm Metastasis
- Oncogene Proteins
- Phenotype
- Plasmids
- Rats
- S100 Calcium-Binding Protein A4
- S100 Proteins