Article
Induction of metastatic ability in a stably diploid benign rat mammary epithelial cell line by transfection with DNA from human malignant breast carcinoma cell lines.
Cancer research - 15 May 1994
Davies B R, Barraclough R, Rudland P S
Abstract excerpt
Transfection of the stably diploid rat mammary epithelial cell line, Rama 37, which yields nonmetastasizing, adenomatous tumors in syngeneic rats with HindIII-fragmented DNA from malignant or nonmalignant human breast epithelial cell lines and the drug-resistance plasmid pSV2neo, yields transform...
Topics
- Animals
- Base Sequence
- Blotting, Southern
- Breast Neoplasms
- Cell Transformation, Neoplastic
- DNA, Neoplasm
- Diploidy
- Female
- Humans
- Injections, Subcutaneous
- Mammary Neoplasms, Experimental
- Molecular Sequence Data
