Different malignant phenotypes induced in a stable, subdiploid, benign epithelial clone by DNA transfection.

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Article

Different malignant phenotypes induced in a stable, subdiploid, benign epithelial clone by DNA transfection.

Anticancer research - 1 Jan 2000

Gibbins J R, Nicholson T R, Vozab R J, Ying B, Messerle K R

Abstract excerpt

Progression to malignancy in carcinomas has been studied in a stable, benign, subdiploid, cloned epithelial cell line (A5P/B10) sensitive to Geneticin at 100 micrograms/ml. A total of 28 cell lines were selected for Geneticin - resistance and inoculated into the footpads of syngeneic animals foll...

Topics

Animals
Azacitidine
Cell Division
Cell Line
Cell Transformation, Neoplastic
DNA, Neoplasm
Epithelium
Genes, ras
Gentamicins
Hydroxyurea
Lymphatic Metastasis
Mammary Neoplasms, Experimental
Neoplasm Metastasis
Neoplasms, Experimental
Phenotype
Plasmids
Rats
Rats, Inbred Strains

Source

Open in PubMed

Identifiers

PMID: 1708218

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1708218-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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