Article
Identification of peplomer cleavage site mutations arising during persistence of MHV-A59.
Advances in experimental medicine and biology - 1 Jan 1993
Gombold J L, Hingley S T, Weiss S R
Abstract excerpt
Primary mouse glial cell cultures were infected with mouse hepatitis virus strain A59 (MHV-A59) and maintained over an 18 week period. Viruses isolated from these cultures 16-18 weeks postinfection produce small plaques on fibroblasts and cause only minimal levels of cell-to-cell fusion at times...
Topics
- Animals
- Astrocytes
- Base Sequence
- Brain
- Cell Fusion
- Cells, Cultured
- Cytopathogenic Effect, Viral
- Defective Viruses
- Membrane Glycoproteins
- Mice
- Mice, Inbred C57BL
- Molecular Sequence Data
- Murine hepatitis virus
- Neuroglia
- Phenotype
- Protein Precursors
- Spike Glycoprotein, Coronavirus
- Viral Envelope Proteins
