Hepatitis mutants of mouse hepatitis virus strain A59.

doi:10.1007/978-1-4615-1899-0_92

Back to search

Article

Hepatitis mutants of mouse hepatitis virus strain A59.

Advances in experimental medicine and biology - 1 Jan 1995

Hingley S T, Gombold J L, Lavi E, Weiss S R

Abstract excerpt

MHV-A59 causes acute meningoencephalitis and hepatitis in susceptible mice, and a persistent productive, but nonlytic, infection of cultured glial cells. We have shown previously that viruses isolated from persistently infected glial cell cultures have a fusion-defective phenotype and were impair...

Topics

Animals
Brain
Coronavirus Infections
Genes, Viral
Hepatitis, Viral, Animal
Liver
Membrane Glycoproteins
Mice
Mice, Inbred C57BL
Murine hepatitis virus
Mutation
Spike Glycoprotein, Coronavirus
Viral Envelope Proteins
Virus Replication

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.