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Article

The spike protein of murine coronavirus regulates viral genome transport from the cell surface to the endoplasmic reticulum during infection.

Journal of virology - 1 Oct 2009

Zhu Hongqing, Yu Dongdong, Zhang Xuming

Abstract excerpt

We observed that the nonfusogenic mouse hepatitis virus (MHV) strain MHV-2 reached a titer of approximately 2 log10 higher than that of the fusogenic strain A59 in astrocytoma DBT cells. To determine whether the spike protein is responsible for the difference, a recombinant virus, Penn-98-1, that contains the A59 genome with a spike from MHV-2 was used to infect DBT cells. Results showed that Penn-98-1 behaved...

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Source

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Identifiers

PMID: 19570858
DOI: 10.1128/JVI.00956-09
PMCID: PMC2753108

Genes

DBT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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