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Mutation in the UL97 open reading frame of human cytomegalovirus strains resistant to ganciclovir

1 Jul 1994

Abstract excerpt

The same point mutation in the human cytomegalovirus UL97 open reading frame was found in three independently isolated ganciclovir-resistant mutants of strain AD169. Point mutations in the DNA polymerase genes of these strains have been previously identified (N.S. Lurain, K.D. Thompson, E.W. Holmes, and G.S. Read, J. Virol. 66:7146-7152, 1992). All three strains are, therefore, double mutants. To determine the...

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PMID: 8207815
DOI: 10.1128/jvi.68.7.4427-4431.1994

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Mutation in the UL97 open reading frame of human cytomegalovirus strains resistant to ganciclovirPMID 8207815Read ↗

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