Article
Mutations in the human cytomegalovirus UL27 gene that confer resistance to maribavir.
Journal of virology - 1 Jul 2004
Chou Sunwen, Marousek Gail I, Senters Anne E, Davis Michelle G, Biron Karen K
Abstract excerpt
Previous drug selection experiments resulted in the isolation of a human cytomegalovirus (CMV) UL97 phosphotransferase mutant resistant to the benzimidazole compound maribavir (1263W94), reflecting the anti-UL97 effect of this drug. Three other CMV strains were plaque purified during these experiments. These strains showed lower-grade resistance to maribavir than the UL97 mutant. Extensive DNA sequence analyses...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
