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Article

Activation of human factor V by meizothrombin.

The Journal of biological chemistry - 10 Jun 1994

Tans G, Nicolaes G A, Thomassen M C, Hemker H C, van Zonneveld A J, Pannekoek H, Rosing J

Abstract excerpt

A recombinant human prothrombin was prepared in which Arg155 was replaced by Ala. The recombinant prothrombin was converted into a meizothrombin derivative (R155A meizothrombin) that was resistant to autocatalytic removal of the fragment 1 domain. R155A meizothrombin appeared to be a potent factor V activator in reaction mixtures that contained negatively charged phospholipid vesicles. Factor V activation by...

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PMID: 8206891

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Activation of human factor V by meizothrombin.PMID 8206891Read ↗

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