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Article

Coagulation factor V: an old star shines again.

Thrombosis and haemostasis - 1 Jul 1997

Rosing J, Tans G

Abstract excerpt

Blood coagulation factor V plays an important role in the regulation of thrombin formation. Activation of factor V by traces of activated coagulation factors (thrombin, factor Xa or meizothrombin) yields factor Va, the non-enzymatic cofactor of the prothrombinase complex. Since factor Va accelerates prothrombin activation under physiological conditions more than 10(4)-fold it is not surprising that...

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PMID: 9198191

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APC

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Coagulation factor V: an old star shines again.PMID 9198191Read ↗

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Factor V is an anticoagulant cofactor for activated protein C during inactivation of factor Va.Semantic proximity Read ↗

Early days of APC resistance and FV Leiden.Semantic proximity Read ↗

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Re-evaluation of the role of the protein S-C4b binding protein complex in activated protein C-catalyzed factor Va-inactivation.Semantic proximity Read ↗

An antifibrinolytic mechanism describing the prothrombotic effect associated with factor VLeiden.Semantic proximity Read ↗

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