Article
p53 mutation in B-cell lymphoid neoplasms with reference to oncogene rearrangements associated with chromosomal translocations.
Japanese journal of cancer research : Gann - 1 Sept 1996
Akasaka T, Muramatsu M, Kadowaki N, Ohno H, Ishizaki K, Yamabe H, Fukuhara S, Okuma M
Abstract excerpt
We investigated mutations of the p53 tumor suppressor gene in B-cell lymphoid neoplasms with reference to oncogene rearrangements associated with specific chromosomal translocations. These included 15 patients with a BCL1/PRAD1 gene rearrangement and/or PRAD1 overexpression, 45 with a BCL2 rearrangement, 2 with a BCL3 rearrangement, 24 with a BCL6 rearrangement, and 6 with both BCL2 and BCL6 rearrangements....
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