Article
p53 mutation in B-cell lymphoid neoplasms with reference to oncogene rearrangements associated with chromosomal translocations.
Japanese journal of cancer research : Gann - 1 Sept 1996
Akasaka T, Muramatsu M, Kadowaki N, Ohno H, Ishizaki K, Yamabe H, Fukuhara S, Okuma M
Abstract excerpt
We investigated mutations of the p53 tumor suppressor gene in B-cell lymphoid neoplasms with reference to oncogene rearrangements associated with specific chromosomal translocations. These included 15 patients with a BCL1/PRAD1 gene rearrangement and/or PRAD1 overexpression, 45 with a BCL2 rearra...
Topics
- Cyclin D1
- Cyclins
- Gene Rearrangement
- Genes, p53
- Humans
- Leukemia, B-Cell
- Lymphoma, B-Cell
- Mutation
- Oncogene Proteins
- Oncogenes
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Translocation, Genetic
- Tumor Cells, Cultured
