Article
The power of interval mapping of quantitative trait loci, using selected sib pairs.
American journal of human genetics - 1 Oct 1994
Cardon L R, Fulker D W
Abstract excerpt
The interval-mapping procedure of Fulker and Cardon for analysis of a quantitative-trait loci (QTL) is extended for application to selected samples of sib pairs. Phenotypic selection of sib pairs, which is known to yield striking increases in power when a single marker is used, provides further increases in power when the interval-mapping approach is used. The greatest benefits of the combined approach are...
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