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Article

The power of interval mapping of quantitative trait loci, using selected sib pairs.

American journal of human genetics - 1 Oct 1994

Cardon L R, Fulker D W

Abstract excerpt

The interval-mapping procedure of Fulker and Cardon for analysis of a quantitative-trait loci (QTL) is extended for application to selected samples of sib pairs. Phenotypic selection of sib pairs, which is known to yield striking increases in power when a single marker is used, provides further increases in power when the interval-mapping approach is used. The greatest benefits of the combined approach are...

Topics

Algorithms
Alleles
Gene Frequency
Genes, Recessive
Genetic Carrier Screening
Genetics, Medical
Genotype
Humans
Mathematics
Models, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7942859
PMCID: PMC1918307

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7942859-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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