Article
Sib mating designs for mapping quantitative trait loci.
Genetica - 1 Jan 1998
Xie C, Gessler D D, Xu S
Abstract excerpt
The power to separate the variance of a quantitative trait locus (QTL) from the polygenic variance is determined by the variability of genes identical by descent (IBD) at the QTL. This variability may increase with inbreeding. Selfing, the most extreme form of inbreeding, increases the variability of the IBD value shared by siblings, and thus has a higher efficiency for QTL mapping than random mating. In...
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