Sib mating designs for mapping quantitative trait loci.

doi:10.1023/a:1003220609636

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Article

Sib mating designs for mapping quantitative trait loci.

Genetica - 1 Jan 1998

Xie C, Gessler D D, Xu S

Abstract excerpt

The power to separate the variance of a quantitative trait locus (QTL) from the polygenic variance is determined by the variability of genes identical by descent (IBD) at the QTL. This variability may increase with inbreeding. Selfing, the most extreme form of inbreeding, increases the variabilit...

Topics

Animals
Breeding
Chromosome Mapping
Computer Simulation
Family Characteristics
Genetic Markers
Genetic Variation
Humans
Likelihood Functions
Models, Genetic
Monte Carlo Method
Pedigree

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