Article
[DNA typing of HLA antigen in patients with autoimmune thyroid disease using the PCR-SSOP method].
Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 1994
Tamai H, Kimura A
Abstract excerpt
The purpose of this study was to investigate HLA-linked genetic factors involved in the pathogenesis of autoimmune thyroid disease such as Graves' disease and Hashimoto's thyroiditis. In 76 Graves' disease patients and 317 healthy Japanese controls, HLA-A, -B, -C, DR and DQ specificities were determined by serologic typing and HLA-DPB1 alleles were typed by DNA typing using the PCR-SSOP method. The frequencies of...
Topics
- Alleles
- DNA
- Genetic Markers
- Graves Disease
- HLA Antigens
- Humans
- Polymerase Chain Reaction
- Thyroiditis, Autoimmune
