Article
[Relevance of CYP27B1 gene promoter polymorphism to autoimmune thyroid diseases].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 Apr 2008
Yang Jing, Xiong Feng
Abstract excerpt
OBJECTIVE: To investigate the relationship between CYP27B1 gene promoter polymorphism and autoimmune thyroid diseases. METHODS: A case-control study including 158 patients with Graves' disease (GD), 174 patients with Hashimoto's thyroiditis (HT) and 172 matched controls was conducted. Three genotypes of CYP27 B1 gene -1260 site (CC, AA and AC) were determined by restriction fragment length polymorphism (PCR-RFLP)...
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