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Article

Resistance to autoimmune thyroid disease is associated with HLA-DQ.

The Journal of clinical endocrinology and metabolism - 1 Jan 1994

Tamai H, Kimura A, Dong R P, Matsubayashi S, Kuma K, Nagataki S, Sasazuki T

Abstract excerpt

Genotypes of DQA1 and DQB1 genes were determined by polymerase chain reaction followed by dot blot hybridization with sequence-specific oligonucleotide probes in 105 patients with goitrous autoimmune thyroiditis (Hashimoto's thyroiditis) and in 67 patients with Graves' disease to investigate whether specific DQ alleles were associated with susceptibility or resistance to autoimmune thyroid diseases. Hashimoto's...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8288722
DOI: 10.1210/jcem.78.1.8288722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resistance to autoimmune thyroid disease is associated with HLA-DQ.PMID 8288722Read ↗

Susceptibility and resistance alleles of human leukocyte antigen (HLA) DQA1 and HLA DQB1 are shared in endocrine autoimmune disease.Semantic proximity Read ↗

[DNA typing of HLA antigen in patients with autoimmune thyroid disease using the PCR-SSOP method].Semantic proximity Read ↗

Susceptibility to thyroid autoimmune disease: molecular analysis of HLA-D region genes identifies new markers for goitrous Hashimoto's thyroiditis.Semantic proximity Read ↗

Analysis of HLA class II genes in Hashimoto's thyroiditis reveals differences compared to Graves' disease.Semantic proximity Read ↗

Human histocompatibility leukocyte antigen-DQA1*0501 allele associated with genetic susceptibility to Graves' disease in a Caucasian population.Semantic proximity Read ↗

Major histocompatibility complex class II (DRB1*, DQA1*, and DQB1*) and DRB1*04 subtypes' associations of Hashimoto's thyroiditis in a Greek population.Semantic proximity Read ↗

HLA-DR/DQ gene variation in nongoitrous autoimmune thyroiditis at the serological and molecular level.Semantic proximity Read ↗

HLA-A2 phenotype may be protective against Graves' disease but not against Hashimoto's thyroiditis in Caucasians.Semantic proximity Read ↗

Association of the HLA-DRB1*0301 and HLA-DQA1*0501 alleles with Graves' disease in a population representing the gene contribution from several ethnic backgrounds.Semantic proximity Read ↗

HLA-DQB1-associated susceptibility that distinguishes Hashimoto's thyroiditis from Graves' disease in type I diabetic patients.Semantic proximity Read ↗

HLA DQA1*0501 and DRB1*0301 antigens do not independently convey susceptibility to Graves' disease.Semantic proximity Read ↗

Susceptibility to autoimmune thyroiditis in Down's syndrome is associated with the major histocompatibility class II DQA 0301 allele.Semantic proximity Read ↗

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