HLA-A and -DRB4 genes in controlling the susceptibility to Hashimoto's thyroiditis.

doi:10.1016/0198-8859(94)00089-9

Back to search

Article

HLA-A and -DRB4 genes in controlling the susceptibility to Hashimoto's thyroiditis.

Human immunology - 1 Feb 1995

Wan X L, Kimura A, Dong R P, Honda K, Tamai H, Sasazuki T

Abstract excerpt

HLA-linked genetic factors involved in the pathogenesis of HT were studied in 71 patients with HT by serologic typing for HLA-A, -B, -C, -DR, and -DQ specificities and by DNA typing for HLA-DRB1, -DRB3, -DRB4, -DRB5, -DQA1, -DQB1, AND -DPB1 genes using the PCR-SSOP method. Typing results demonstr...

Topics

Genetic Predisposition to Disease
HLA-A Antigens
HLA-DR Antigens
HLA-DRB4 Chains
Histocompatibility Testing
Humans
Polymerase Chain Reaction
Thyroiditis, Autoimmune

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.