Article
HLA-A and -DRB4 genes in controlling the susceptibility to Hashimoto's thyroiditis.
Human immunology - 1 Feb 1995
Wan X L, Kimura A, Dong R P, Honda K, Tamai H, Sasazuki T
Abstract excerpt
HLA-linked genetic factors involved in the pathogenesis of HT were studied in 71 patients with HT by serologic typing for HLA-A, -B, -C, -DR, and -DQ specificities and by DNA typing for HLA-DRB1, -DRB3, -DRB4, -DRB5, -DQA1, -DQB1, AND -DPB1 genes using the PCR-SSOP method. Typing results demonstrated significant positive associations of HT with HLA-A2 and -DRB4*0101 (DR53) (p < 0.01, RR = 2.03, EF = 0.61 and p <...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
