Article
Association of HLA alleles with autoimmune thyroid disease in Korean children.
Hormone research in paediatrics - 1 Jan 2011
Cho Won Kyoung, Jung Min Ho, Choi Eun-Jeong, Choi Hee-Baeg, Kim Tai-Gyu, Suh Byung-Kyu
Abstract excerpt
BACKGROUNDS: Data regarding genetics of Hashimoto's disease (HD) and Graves' disease (GD) in Korean children are lacking. METHODS: 73 patients with autoimmune thyroid disease (AITD; HD 32, GD 41) were recruited. We analyzed human leukocyte antigen (HLA) class I and HLA-DRB1 by PCR-SSP, and compared them with those of 159 controls. RESULTS: In AITD, the allele frequencies of HLA-A*02, -B*46, -Cw*01 and -DRB1*08...
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