HLA class II alleles in Japanese patients with Graves' disease: weak associations of HLA-DR and -DQ.

doi:10.1507/endocrj.41.599

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Article

HLA class II alleles in Japanese patients with Graves' disease: weak associations of HLA-DR and -DQ.

Endocrine journal - 1 Dec 1994

Katsuren E, Awata T, Matsumoto C, Yamamoto K

Abstract excerpt

To elucidate the associations of the HLA class II alleles with Graves' disease (GD), we examined DRB1, DQA1, DQB1 alleles in 62 Japanese GD patients and 142 control subjects by the PCR-SSOP (polymerase chain reaction-sequence specific oligonucleotide probes) method. We found that DRB1*0803 (P < 0...

Topics

Alleles
Gene Frequency
Genes, MHC Class II
Graves Disease
HLA-DQ Antigens
HLA-DR Antigens
Haplotypes
Humans
Japan
Oligonucleotide Probes
Polymerase Chain Reaction

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