Article
Allelotype analysis of esophageal squamous cell carcinoma.
Cancer research - 1 Jun 1994
Shibagaki I, Shimada Y, Wagata T, Ikenaga M, Imamura M, Ishizaki K
Abstract excerpt
In previous studies, we have shown that allelic loss on chromosome 17p, on which the p53 gene is located, is very frequent, and loss-of-function mutations of the p53 gene are closely associated with the tumorigenesis of esophageal cancer. In this study, we performed allelotype analysis to investi...
Topics
- Alleles
- Base Sequence
- Carcinoma, Squamous Cell
- Chromosome Mapping
- Esophageal Neoplasms
- Gene Deletion
- Genes, APC
- Genes, Tumor Suppressor
- Humans
- Molecular Sequence Data
- Mutation
- Survival Rate