Article
Allelotype analysis of esophageal squamous cell carcinoma.
Cancer research - 1 Jun 1994
Shibagaki I, Shimada Y, Wagata T, Ikenaga M, Imamura M, Ishizaki K
Abstract excerpt
In previous studies, we have shown that allelic loss on chromosome 17p, on which the p53 gene is located, is very frequent, and loss-of-function mutations of the p53 gene are closely associated with the tumorigenesis of esophageal cancer. In this study, we performed allelotype analysis to investigate whether other tumor suppressor genes are also involved in esophageal cancer. Using 55 polymorphic DNA markers...
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