Article
Allelotype analysis of esophageal adenocarcinomas: evidence for the involvement of sequences on the long arm of chromosome 4.
Cancer research - 1 Oct 1996
Hammoud Z T, Kaleem Z, Cooper J D, Sundaresan R S, Patterson G A, Goodfellow P J
Abstract excerpt
The incidence of esophageal adenocarcinoma has increased dramatically over the past 20 years. The causes for this change in incidence and the genetic defects that underlie tumorigenesis are unknown. We performed loss of heterozygosity (LOH) studies in esophageal adenocarcinomas in an effort to map the location of tumor suppressor genes involved in the initiation or progression of this cancer. A genome-wide search...
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