Allelotype analysis of esophageal adenocarcinomas: evidence for the involvement of sequences on the long arm of chromosome 4.

Article

Allelotype analysis of esophageal adenocarcinomas: evidence for the involvement of sequences on the long arm of chromosome 4.

Cancer research - 1 Oct 1996

Hammoud Z T, Kaleem Z, Cooper J D, Sundaresan R S, Patterson G A, Goodfellow P J

Abstract excerpt

The incidence of esophageal adenocarcinoma has increased dramatically over the past 20 years. The causes for this change in incidence and the genetic defects that underlie tumorigenesis are unknown. We performed loss of heterozygosity (LOH) studies in esophageal adenocarcinomas in an effort to ma...

Topics

Adenocarcinoma
Alleles
Chromosomes, Human, Pair 4
DNA, Neoplasm
Esophageal Neoplasms
Genes, Tumor Suppressor
Humans
Microsatellite Repeats
Sequence Deletion

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