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Article

Genome-wide loss of heterozygosity and copy number alteration in esophageal squamous cell carcinoma using the Affymetrix GeneChip Mapping 10 K array.

BMC genomics - 29 Nov 2006

Hu Nan, Wang Chaoyu, Hu Ying, Yang Howard H, Kong Li-Hui, Lu Ning, Su Hua, Wang Quan-Hong, Goldstein Alisa M, Buetow Kenneth H, Emmert-Buck Michael R, Taylor Philip R, Lee Maxwell P

Abstract excerpt

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is a common malignancy worldwide. Comprehensive genomic characterization of ESCC will further our understanding of the carcinogenesis process in this disease. RESULTS: Genome-wide detection of chromosomal changes was performed using the Affymetrix GeneChip 10 K single nucleotide polymorphism (SNP) array, including loss of heterozygosity (LOH) and copy number...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17134496
DOI: 10.1186/1471-2164-7-299
PMCID: PMC1687196

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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