Article
Functional domains of c-Myc involved in the commitment and differentiation of murine erythroleukemia cells.
Oncogene - 1 Feb 1993
Ohmori Y, Tanabe J, Takada S, Lee W M, Obinata M
Abstract excerpt
In the early event of the induction of mouse erythroleukemia (MEL) cell differentiation, c-myc mRNA levels show a drastic change. The elevated expression of a transfected c-myc gene inhibits the commitment and differentiation of MEL cell transformants. In the present work, we have introduced human c-myc mutants into MEL cells under the inducible promoter to define the functional domains of c-Myc involved in...
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